Degradation polymers Polyethylene glycol

Jens G (1996) Degradation of polyethylene glycol. A study of the reaction mechanism in a model molecule Tetraethylene glycol. Polym Degrad Stabil 52(3) 217-222... [Pg.39]

Han S, Kim C, Kwon D (1997) Thermal/oxidative degradation and stabilization of polyethylene glycol. Polymer 38(2) 317-323... [Pg.39]

Poly(e-caprolactone) (PCL) is synthesized by anionic, cationic or coordination polymerization of e-caprolactone. Degradable block copolymers with polyethylene glycol, diglycolide, substituted caprolactones and /-valerolactone can also be synthesized. Like the lactide polymers, PCL and its copolymers degrade both in vitro and in vivo by bulk hydrolysis, with the degradation rate affected by the size and shape of the device and additives. [Pg.94]

Polyacetal polymers containing polyethylene glycol have been prepared which are stable at physiological pH but which readily degrade at lower pH s. Bolton Hunter reagent conjugates prepared from these materials showed a favorable biodistribution profile of the product. [Pg.31]

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