Degradation control over rate

Failure to control the rate of degradation of cyclins could lead to their over-expression, increasing the risk of tumour development. 

EB Second, control over the rate of degradation is necessary. Not all consumer items made of a photodegradable polymer would be stored or used under the same conditions. Some of them might begin to degrade prematurely, causing inconvenience or even safety concerns. 

A study in coronary patients has shown that fibrinogen levels are Increased over normal controls ° and that fibrinolytic activity is also decreased in these patients.The rate of degradation of fibrinogen is inhibited in rats fed an atherogenic diet. It would seem reasonable then that some control over the clinical outcome of atherosclerosis could be had by the use of fibrinolytic agents. The enzymes streptokinase and urokinase continue to be evaluated with some benefits reported in the therapy of acute Thromboembolism.Phenformin is still the only drug of interest as a fibrinolytic agent other than the enzymes and CPIB mentioned earlier. 

Characteristics such as rate of degradation, swelling, and mechanical strength can he precisely controlled hy a proper combination of the two copolymer segments. Thus, a tight control over the release rates of diverse molecules, including vitamins, peptides, and proteins, can be obtained (50,54,56,58). 

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