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Definitive notes, authentication

The metabolism of atropine (227) by rat and guinea pig liver microsomes has been studied (197-199). French workers noted the formation of nora-tropine (229), apoatropine (233), and a phenolic metabolite formulated as the ortho-phenol 230 (197, 198) by liver microsomes from the rat, and they reported that hydrolysis of the ester function of 227 did not occur with enzymes from this source (197, 198). The structure of 229 was determined by TLC comparisons of the metabolite with an authentic sample and by correlation of the formation of the metabolite with the release of formaldehyde in the incubation mixture. The structure of 233 was deduced by TLC and UV spectral comparisons of isolated metabolite with authentic sample, and the phenol 230 was identified by TLC color reactions and by comparison with a phenolic sample obtained by Udenfried oxidation of atropine. In the absence of more definitive data on the phenolic products of this reaction, the structure 230 proposed for the phenolic metabolite of atropine... [Pg.393]

Note that the functional notation does not treat the case i > N. The following formal security definitions implicitly take Property c) from Definition 7.1 for granted, i.e., they do not treat what a signer s entity might do in authentications after the message bound has been reached, because it does not do anything. [Pg.161]

As a practical application of these results, we note that the oldest wax sculpture in the world in the collections of the MetropoUtan Museum of Art was found to be made of modem paraffin (see Figure 6.2). This finding definitely casts doubt about the authenticity of this object because paraffin is a product of the 19th century. For comparison. Figure 6.3 to Figure 6.6 show pyrograms of spermaceti, stearine, candemia, and camauba waxes, respectively. [Pg.110]

Note Both figures with their characteristic zone profiles provide an additional definite authentication for Fructus Xanthii. [Pg.84]

Bifurcation theory studies the changes in the phase space as we vary the parameters of the system. In essence, this is the authentic notion of bifurcation theory proposed originally by Henry Poincare when he studied Hamiltonian systems with one degree of freedom. We must, however, note that this intuitively evident definition is not always sufficient at the contemporary stage of the development of the theory. One needs, in fact, to have an appropriate mathematical foundation to define the notions of the structure of the phase space and the changes in the structure. [Pg.5]


See other pages where Definitive notes, authentication is mentioned: [Pg.944]    [Pg.1204]    [Pg.1204]    [Pg.135]    [Pg.507]    [Pg.30]    [Pg.334]    [Pg.446]    [Pg.135]    [Pg.3589]    [Pg.152]    [Pg.108]    [Pg.388]    [Pg.395]    [Pg.388]    [Pg.313]    [Pg.33]   
See also in sourсe #XX -- [ Pg.944 ]




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