Decanesulfonic acid

Octadecylsilica (Waters Symmetry) 100 x 4.6 mm with 5 mm guard cartridge 0.5% H3PO4, 0.7% triethylamine pH 3.0 buffer/acetonitrile (72/28 ) containing 6 mM 1-decanesulfonic acid 1.8 mL/minute 50 pL for whole blood, 60 pLfor plasma UV at 254 nm 45"C... 

Centrgn, TCA extn, liq-liq partns, 1-decanesulfonic acid addn... 

Increased retention of the analytes can also be achieved by addition of various ion-pair reagents in the mobile phase Tetrabutylammonium cations have typically been used as counter ions, at around pH 6.5, to increase retention and improve the selectivity in the analysis of monobasic penicillins (105, 123). Alkyl-sulfonic acids have been also used to improve the separation of -lactams bearing an amine function in their side chain or having a neutral side chain. Heptanesul-fonic acid (80, 103), decanesulfonic acid (87, 93, 106), dodecanesulfonic acid (77, 107-110), or mixtures of octanesulfonic and dodecanesulfonic acids (73, 75, 78, 79) constitute the principal alkylsulfonic acids used in -lactam analysis. In some applications, heptafluorobutyric acid (74, 76) or sodium thiosulfate (90, 112, 115, 116, 121, 122) has also been used as an ion-pairing reagent. 

The activity is found in erythrocytes, platelets, and lymphocytes, and determination of its value aids in diagnosis of some blood disorders. In this assay, which can readily be used for purine and pyrimidine 5 - and 3 -nucleotidase activities, the nucleoside monophosphate (the substrate) was separated from the nucleoside (the product) using ion-pair reversed-phase HPLC with a mobile phase of 5% methanol-5 mAf potassium dihydrogen phosphate 0.25 mAf 1-decanesulfonic acid was also added to the mobile phase. The elution was carried out at room temperature and the eluent monitored at 254 nm. 

Mobile phase MeCN 10 mm KH2PO4 + 5 mM 1-decanesulfonic acid heptylamine 50 50 ... 

CA mobile phase 60 mM sodium acetate, 2 mM decanesulfonic acid, 0.1 roM Na2EDTA, and acetonitrile (see below and Note 5). To make 1L, dissolve 0.19 g of Na2EDTA (dihydrate) in approx 50 mL of punfled water, then add 8.2 g of... 

Decanethiol is efficiently oxidized to decanesulfonic acid (97% yield) by aqueous Oxone. In a similar manner an acylthio function was converted into the potassium sulfonate salt, as shown in eq 28. ... 

Burdon J et al. (1957) Fluorinated sulphtmic acids. Part I. Perfluoromethane-.octane-, and -decanesulfonic acids and their simple derivatives. J Chem Soc 2574-2578... 

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