Dearomatization Reactions An Overview

Department of Chemistry, University of Iowa, Iowa City, lA, USA 

In this chapter, an overview of dearomatization tactics employed in organic synthesis is presented. The material is organized according to mechanistic considerations and includes discussion of conventional as well as transition metal-mediated dearomatization reactions, with particular emphasis accorded to asymmetric processes. This chapter highlights the most common dearomatization reactions encountered in synthesis (with the exclusion of the Birch reduction—the topic of another chapter in this volume) and is not meant to provide a comprehensive treatise on the subject. Only dearomatization reactions of carbocyclic arenes are discussed. 

Arene Chemistry Reaction Mechanisms and Methods for Aromatic Compounds, First Edition. Edited by Jacques Mortier. 

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