Dantrolene Alcohol

C5H4O2 98-01-1) see Azimilide hydrochloride Dantrolene Piperidolate furfuryl alcohol... 

There is a very great demand for drugs for the relief of anxiety. This was formerly met by the use of alcohol, bromides or barbiturates, which carried the risk of abuse or dangerous toxicity. The first of the modern minor tranquilizers, introduced from 1946 onwards, were drugs described as skeletal muscle relaxants. These were mainly derivatives of polyhydric alcohols, but heterocyclic examples included metaxolone (161), which is related to the aryl ethers of glycerol, chlorzoxazone (162) and chlormezanone (163). Dantrolene sodium (164) is a muscle relaxant and CNS depressant. 

The manufacturer of dantrolene advises caution if it is given with alcohoP and the patient information leaflet suggests that alcohol should be avoided because it may increase drowsiness. ... 

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