Danish List of Undesirable Substances

The Danish List of Undesirable Substances is a list of chemicals of concern that the government believes should be avoided to the extent feasible in commerce. Using a systematic analysis, substances are selected automatically if they meet some clear and defined criteria, for example, problematic classifications, because they are imder suspicion for being PBT/vPvB (Persistent, Bioaccumulative, Toxic/very Persistent, very Bio accumulative) or endocrine-disrupting. 

If these criteria are fulfilled, then the R53 phrase is required unless e.g. there is evidence of an absence of chronic toxicity effects at the solubility limit. The underlying concern is the possibility that such substances might bioconcentrate in aquatic species to harmful levels. This issue has also been raised in the case of the Danish List of Undesirable Substances which is discussed later in Sec. 23.6.3. 

---