Cytotoxic guanidine-alkaloids

Kourany-Lefoll, E. Laprevote, O. Sevenet, T. Montagnac, A. Pais, M. Debitus, C. (1994) Phloeodictines A1-A7 and C1-C2, Antibiotic and Cytotoxic Guanidine Alkaloids from the New Caledonian Sponge, Phloeodictyon sp. Tetrahedron, 50,3415-26. 

Palagiano, E. De Marino, S. Minale, L. Riccio, R. Zollo, F. lorizzi, M. Carre, J.B. Debitus, C. Lucarain, L. Provost, J. (1995) Ptilomycalin A, crambescidin 800 and related new highly cytotoxic guanidine alkaloids from the starfishes Fromia monilis and Celerina heffemani. Tetrahedron, 51, 3675-82. 

Bouaicha, N., Amade, P Fuel, D., and Roussakis, C. (1994) Zarzissine, a new cytotoxic guanidine alkaloid from the Mediterranean sponge Anchinoe paupertas. J. Nat. Prod., 57, 1455-1457. 

Ptilomycalin A (96) is a novel polycyclic guanidine alkaloid isolated from the sponge Ptilocaulis spiculifer (31). It is highly cytotoxic, antifungal, and antiviral. The related alkaloids were reported from the Mediterranean sponge Crambe crambe that also contains other types of guanidine alkaloids such as... 

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