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Cytidine selective methylation with

Another approach that can be used to incorporate Ru(bpy)2 -type molecules into DNA oligomers is to chemically modify a cytidine or thymidine base with a linker arm terminating in a primary amine. This terminal amine functionality can then be selectively reacted with the -hydroxysuccinimide ester of 4 -carboxy-4 -methyl-2,2 -bipyridine to form bipyridine-labeled oligomers. These oligomers react with Ru(bpy)2(H20)2 to give covalently attached derivatives of the type... [Pg.208]

N. K. Kochetkov, E. I. Budowsky, and R. P. Shibaeva, The selective reaction of O-methyl-hydroxylamine with the cytidine nucleus, Biochim. Biophys. Acta, 68 (1963) 493-496. [Pg.19]

See other pages where Cytidine selective methylation with is mentioned: [Pg.66]    [Pg.265]    [Pg.235]    [Pg.255]    [Pg.59]    [Pg.70]    [Pg.78]    [Pg.153]    [Pg.66]    [Pg.314]    [Pg.589]    [Pg.180]    [Pg.341]    [Pg.336]    [Pg.200]    [Pg.336]   


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