Cystic fibrosis gastrointestinal tract

In patients whose maldigestion is difficult to control, other underlying conditions should be considered, such as noncompliance, infections of the gastrointestinal tract, celiac disease, lactose deficiency, inflammatory bowel disease, anatomical abnormalities, diabetes, and liver cirrhosis. This question is complicated by the abundance of small intestinal viscous glycoproteins in cystic fibrosis, prolonged intestinal transit times, which may provoke bacterial overgrowth [104], and absorption of the enzymes in their macromolecular form [105]. 

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