Cydohexyl iodide

Cyddhexylidenecarbene, 30 Cydohexyl iodide, 557 Cyclohexyl metaborate trimer, 112... 

Replacing cydohexyl bromide with cydohexyl iodide. 

The effect of the leaving group was briefly examined but cinnamyl bromide gave a substantially lower ee (38%). Cinnamyl dimethyl phosphonate or acetate gave very poor results. The cydohexyl-substituted allylic acetate 21 on the other hand afforded a completdy y-selective reaction but the product turned out to be racemic. Changing the Grignard reagent halide from bromide to either chloride or iodide resulted in very low ees. 

Determine the percentage of unreacted cydohexyl bromide in the sample mixture from the chromatogram for parameters 1,2, and 3. Determine the percentage of cydohexyl chloride and iodide in parameters 4 and 5, respectively. 

The Calculations Using an Internal Standard. The calculations allow us to compare the amount (%) of cydohexyl bromide (or chloride or iodide) reacted at the 30-min time point for each of the different reaction parameters. 

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