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Cyclosporin food-drug interactions

Drug/Food interactions Administration of food with A/eora/decreases the ADC and Cmax of cyclosporine. A high-fat meal consumed within 30 minutes of Neoral administration decreased the AUC by 13% and Cmax by 33%. The effects of a low-fat meal were similar. In addition, do not take cyclosporine simultaneously with grapefruit juice unless specifically instructed to do so trough cyclosporine concentrations may be increased. [Pg.1968]

Lopinavir/Ritonavir (Kaletra) [Anrirelroviral/Protease Inhibitor] Uses HIV Infxn Action Protease inhibitor Dose Adults. Tx naive 2 tab PO daily or 1 tab PO bid Tx experiencedpt 1 tab PO bid (T dose if w/ amprenavir, efavirenz, fosamprenavir, nelfinavir, nevirapine) Peds. 7-15 kg 12/3 mg/kg PO bid 15-40 kg 10/2.5 mg/kg PO bid >40 kg Adult dose w/ food Caution [C, /-] Numerous interactions Contra w/drugs dependent on CYP3A/CYP2D6 (Table VI-8) Disp Tab, soln SE Avoid disulfiram (soln has EtOH), metronidazole GI upset, asthenia, T cholesterol/triglycerides, pancreatitis protease metabolic synd Interactions T Effects Wl clarithromycin, erythromycin T effects OF amiodarone, amprenavir, azole andfungals, bepridil, cisapride, cyclosporine, CCBs, ergot alkaloids, flecainide, flurazepam, HMG-CoA reductase inhibitors, indinavir, lidocaine, meperidine, midazolam, pimozide, propafenone, propoxyphene, quinidine, rifabutin, saquinavir, sildenafil, tacrolimus, terfenadine, triazolam, zolpidem 1 effects Wl barbiturates, carbamazepine, dexamethasone, didanosine, efavirenz, nevirapine, phenytoin, rifabutin, rifampin, St. John s wort 1 effects OF OCPs, warfarin EMS Use andarrhythmics and benzodiazepines... [Pg.209]


See other pages where Cyclosporin food-drug interactions is mentioned: [Pg.430]    [Pg.153]    [Pg.167]    [Pg.197]    [Pg.85]    [Pg.287]    [Pg.85]    [Pg.425]    [Pg.439]    [Pg.85]    [Pg.475]    [Pg.195]    [Pg.9]    [Pg.176]    [Pg.199]    [Pg.209]    [Pg.304]    [Pg.315]    [Pg.148]    [Pg.7]    [Pg.101]    [Pg.176]    [Pg.199]    [Pg.304]    [Pg.315]    [Pg.148]    [Pg.278]    [Pg.193]    [Pg.7]    [Pg.101]    [Pg.176]    [Pg.199]    [Pg.209]    [Pg.304]    [Pg.315]    [Pg.521]   
See also in sourсe #XX -- [ Pg.123 ]




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Cyclosporin

Cyclosporin/cyclosporine

Cyclosporine drug interactions

Cyclosporines

Cyclosporins

Cyclosporins Cyclosporin

Food interactions

Food-drug interactions

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