Cyclopropanes Diels-Alder

Example of Cyclopropanation, Diels-Alder Reaction, Nucleophilic Allylic Substitution... 

Keywords N,N-Containing ligands Asymmetric catalysis Cyclopropanation Diels-Alder reaction Nucleophilic allylic substitution... 

In this article, special attention has been paid to cyclopropanations, Diels-Alder reactions, and nucleophilic substitutions, for which numerous works have been devoted to the use of Ar,N-containing ligands. Other classical reactions allowing the formation of a new C - C bond have been omitted here (e.g., Michael-type additions or aldol reactions) where they have also been, to a lesser extent, efficiently performed using nitrogen-containing ligands. 

Schulz E (2005) Use of JV,JV-Coordinaling Ligands in Catalytic Asymmetric C-C Bond Formations Example of Cyclopropanation, Diels-Alder Reaction, Nucleophilic Allylic Substitution. 15 93-148... 

Keywords Absolute configuration, Amines, Amino acids, Carbenes, Cascade reactions, 2-chloro-2-cyclopropylideneacetates. Combinatorial libraries. Cycloadditions, Cyclobutenes, Cyclopropanes, Diels-Alder reactions. Heterocycles, Michael additions. Nitrones, Nucleophilic substitutions, Peptidomimetics, Palladium catalysis. Polycycles, Solid phase synthesis, Spiro compounds. Thiols... 

Unsaturated sugar derivatives can undergo a wide range of transformations, in particular, when an enone is involved.31 Examples include cyclopropanations, Diels-Alder cycloadditions and photohydroxymethyl-ation. Many of these reactions proceed with high regio- and stereoselectivity (Scheme 3.6c). 

During the course of the last years, asymmetric/enantiomeric reactions more and more play an increasing role (cf. Section 6.11). Recent publications range from enantioselective hydrogenations [45 m, 47j,r, 51a] or asymmetric hydrofor-mylations [51b] to cyclopropanations, Diels-Alder reactions, or oxidative kinetic resolutions [46d, 49c, 51c, d]. 

The aim of this review is to discuss the contribution of soluble polymer-supported ligands and insoluble polymer-supported ligands to asymmetric catalysis in the field of reduction of C=0 bonds, cyclopropanation, Diels-Alder, alkylation, allylation, dihydroxylations,... 

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