Cyclopentane Dioxane

FIGURE 3 2 Solvent extraction efficiencies (EF) as functions of dielectric constants (D), solubility parameters (6), and polarity parameters (P and E -). Solvents studied silicon tetrachloride, carbon disulfide, n pentane. Freon 113, cyclopentane, n-hexane, carbon tetradiloride, diethylether, cyclohexane, isooctane, benzene (reference, EF 100), toluene, trichloroethylene, diethylamine, chloroform, triethylamine, methylene, chloride, tetra-hydrofuran, l,4 dioxane, pyridine, 2 propanol, acetone, ethanol, methanol, dimethyl sulfoxide, and water. Reprinted with permission from Grosjean. ... 

Cyclohexanol, Cyclopentane, Cyclopentene, 1,2-Dichloroethane, Diethyl phthalate, 1,4-Dioxane, Ethephon. Ethylamine, Ethylene dibromide, Ethylenimine, p-Propiolactone, Tetraethyl pyrophosphate, TCDD, 1,1,1-Trichloroethane, Trichloroethylene, Vinyl chloride Ethylene chlorohydrin, see Bis(2-chloroethyl) ether Ethylenediamine, see Ethylene thiourea. Maneb Ethylene glycol, see Bis(2-chloroethyl) ether, 1,2-Dichloroethane, Ethylene chlorohydrin. Ethylene dibromide... 

Ghung has developed an effective protoeol for the cyclization/silylformylation of 1,6-enynes catalyzed by cobalt/ rhodium nanoparticles (Go2/Rh2). For example, reaction of dimethyl allylpropargylmalonate and triethylsilane catalyzed by Go2/Rh2 in dioxane at 105 °G under GO formed the corresponding silylated cyclopentane... 

In an early step in an enantioselective total synthesis of certain prostaglandins <88T4989,92T10345>, application of the Prins reaction conditions to an unsaturated bicyclic lactone or ether (Equation (11)) afforded tricyclic heterocycles (31) containing cyclopentane-fused tetrahydrofuran and 1,3-dioxane units in 4-10% yield. The major products in each case were bicyclic diacetate derivatives of the starting material. 

Cyclopentan l-Brom-2-tert.-butyl-peroxy- E13/1, 397 (HgBr -> Br) 1,3-Dioxan 2-(4-Brom-butyl)-5,5-dimethyl- E14a/1, 370 (Enol-ether 4- R—OH)... 

DimethyIhexane Cyclopentane Cyclohexane Methanol Ethanol 2-Propanol 2-Methyl-2-propanol Dioxane... 

Five-membered carbocycles Ethoxycyclopropane reacted with TCNE in various sob vents. In dioxane and acetonitrile 3-ethoxy-1,1,2,2-cyclopentane-tetracarbonitrile 375 was the only product. Performing the reaction in benzene also yields a ring-opened enol ether, which reacts further with TCNE . 

They also studied the Pd(PPh3)4-catalyzed intramolecular reaction of an allene moiety with an alkyne in 1,5-alkyne-allene 140 in DMF in the presence of HCO2H affording cyclopentane derivatives 141 [36]. The reaction demonstrated an interesting solvent effect, i.e., the reaction in dioxane afforded a mixture of regioisomers referred to the C=C bond in 141 and 142 (Scheme 59). However, if the terminal alkyne was further substituted with the ethoxycarbonyl group,... 

Genet and Michelet have reported the gold(I)-catalyzed cydization/amination of 1,6-enynes with carboxamides and electron-deficient aromatic amines [27]. Reaction of 1,6-enyne 32 with o-cyanoaniline and a catalytic 1 1 mixture of (PPh3)AuCl and AgSbFg in dioxane at room temperature for 20 h led to isolation of methylene cyclopentane 33 in 93% yield as a single diastereomer (Eq. (11.19)). Gold(I)-catalyzed... 

The alkaline hydrolysis of ethyl c/s-2-hydroxycyclopentanecarboxy-late is 1.8 to 11 times faster than that of ethyl cyclopen tanecarboxy late but this rate difference probably does not arise from intramolecular catalysis since the trans-isomer for which such catalysis is unlikely reacts even faster. The solvent dependence of the rates of both the cis- and lrans-2-hydroxy esters in aqueous dioxan is much smaller than that for ethyl cyclopentane-2-carboxylate and this was tentatively attributed to solvent sorting [53]. 

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