Cyclomalto-octaose

C48H80O40 C3H80 x H20 Cyclomalto-octaose-1-propanol complex, hydrate (CYDXPL)230... 

A. oryzae a-amylase has about the same degree of multiple attack as human salivary a-amylase, i.e. an average of three hydrolytic cleavages per chain encounter. A. oryzae a-amylase is the only common a-amylase known to hydrolyze the cyclic a-(l- 4)-l inked maltodextrins to any extent.25,26 A kinetic analysis revealed that the catalytic constant, k2, increased significantly from 3.3 to 270 to 3270min-1 for cyclomaltohexaose, cyclomaltoheptaose and cyclomalto-octaose, respectively, while the Km was 4.7 M, 10.2 M and 2.4 M, respectively.26... 

C48H8o04o C3H80 H2O Cyclomalto-octaose-1-ptopanol complex, hydrate (CYDXPL) ... 

An approach to the total synthesis of cyclodextrins is outlined. Intramolecular glycosylative cyclizations are investigated as the key step, using appropriately protected malto-ollgosyl fluorides, for successful synthesis of completely protected cyclomalto-hexa-, hepta-, and -octaoses. Deprotection of these Intermediates afforded the desired, unsubsituted cyclodextrins. 

The deoxychlorosucrose O-methyl ether derivatives (2) - (5) have been synthesized from appropriate partially protected precursors. Some partially methylated cyclomalto-hexaose and -octaose compounds are mentioned in Chapter 4. Complete H-and C- n.m.r. assignments have been made for a number of O-methyl derivatives of a- and -D-galactopyranose. 3-0-Stannylmethyl ethers (6) have been reported. ... 

---