Cyclohexanols, nitro

More recently, an efficient transformation of 6-nitro-C-glycofuranosyl derivative 96 into indoline derivatives 99 and 100 has been reported. Treatment of 96 with a base (4% NaOMe or 1% K2C03 in MeOH) at room temperature produced nitro cyclohexanols 97 and 98, via (1-elimination followed by an intramolecular Michael addition (Scheme 31).71... 

Thermolysis of allylic nitro compounds results in the formation of rearranged allyl alcohols the cyclohexene 416, for instance, affords a 4 1 mixture of the cyclohexanol derivatives 417 and 418. It is proposed that the process involves a [2,3] sigmatropic shift of a nitro group (equation 137)451. 

The reaction starts with the oxidation of cyclohexanol to cyclohexanone by nitric acid several paths are then available for cyclohexanone transformation into adipic acid. The main one involves cyclohexanone nitrosation to 2-nitrosocyclohexanone which further reacts with nitric acid to afford 2-nitro-2-nitrosocyclohexanone (Figure 9). The latter gives, upon hydrolysis, 6-nitro-6-hydroximinohexanoic acid which eventually breaks down to adipic acid and nitrous oxide (N2O). 

An example for subtle control by substitution of the phtallocyanine structure is reported by Pattons et al. [193] comparing the activity of FePcY with nitro substituted Fe phthalocyanines in zeolite Y. The electron withdrawing effect of the nitro substiment on the benzene ring was expected to enhance the electrophilic character of the active oxygen species and so to increase the activity. For the oxidation of cyclohexane to cyclohexanone and cyclohexanol with tBHP a 10 fold increase in the turnover frequency (TOF)was found for the nitro substituted complex in zeolite Y in comparison to the unsubstituted [204]. However the nitro substimted Fe phthalocyanines were found to be located at the outer surface of the... 

Let us now consider, a specific case in detail where spectrophotometry has-been used for rate studies. Fagley et aV have studied the thermal decomposition of ort/to-nitrophenylazide to benzofuraxan and nitrogen. o-Nitro-phenylazide exhibits two absorption maxima at 240 mp and 320 mp and a prominent shoulder at 2S5 mp, in cyclohexanol. Benzofuraxan shows only... 

Hydrogenations of nitrobenzene and p-nitrotoluene over supported noble metal catalysts are often investigated as model reactions, as they consist of various elemental reactions vfith different intermediates, which can react with each other, as depicted in the scheme below for p-nitro toluene [150]. At short reaction times, the intermediates are predominantly formed, while complete conversion to p-methyl aniline is achieved at long reaction times. Aniline itself can react further to form side products such as cyclohexanol, cyclohexyl amine, and other species. 

Cyclohexanol added at 18-20° to 6 parts 65-66%-HNO3 at such a rate that no startg. m. accumulates 6-nitro-6-(hydroxyimino)hexanoic acid. Y 97-8%. Z. S. Smolyan et al., Khim. Prom-st 1975, 266 C. A. 83, 58030. 

---