Cyclohexanecarboxylic acid chloride

The protocol is effective in preparation of hydrazides of 5 carbons or less. Cyclopropanecarboxylic acid hydrazide15 and isobutyric acid hydrazide16 were prepared from their corresponding acid chlorides in 64% and 71% yields, respectively. However, when this method was applied to cyclohexanecarboxylic acid chloride, the bis-acylhydrazide was the predominant product, and the mono-acylhydrazide17 was isolated in 25% yield.18... 

Cyclohexanecarboxylic acid chloride, c351 Cyclohexaneethanol, c378 Cyclohexaneethyl acetate, c379 Cyclohexanemethanol, c384 Cyclohexanone cyanohydrin, hi 12 czis -4-Cyclohexene-l,2-dicarboximide, t82... 

Apart from the reaction of cyclohexanecarboxylic acid with methyllithium, cyclohexyl methyl ketone has been prepared by the reaction of cyclohexylmagnesium halides with acetyl chloride or acetic anhydride and by the reaction of methylmagnesium iodide with cyclohexanecarboxylic acid chloride. Other preparative methods include the aluminum chloride-catalyzed acetylation of cyclohexene in the presence of cyclohexane, the oxidation of cyclohexylmethylcarbinol, " the decarboxylation and rearrangement of the glycidic ester derived from cyclohexanone and M)utyl a-chloroj)ropionate, and the catalytic hydrogenation of 1-acetylcycIohexene. "... 

Cyclohexaneacetic acid, c333 Cyclohexanecarboxylic acid chloride, c316... 

Dimethylamine hydrochloride Cyclohexanecarboxylic acid chloride Cyclohexyl-p-chloroethyl ketone... 

Cyclohexanecarboxylic acid chloride may be prepared in the following way a pressure-equalizing addition funnel fitted with a nitrogen inlet tube is attached to a 500-mL, round-bottomed flask which is equipped... 

Refractor vapor-phase chromatograph infrared spectrometer fume hood steam bath pump for reduced pressure distillation thionyl chloride (30 g) cyclopropanecarbox-ylic acid (7 g) and cyclohexanecarboxylic acid (8 g) or cyclopropanecarboxylic acid chloride (8 g) and cyclohexanecarboxylic acid chloride (9 g) o-butanol (6 g) methanol (4 g) ethyl ether (175 mL) saturated aqueous NaffC03 solution (40 mL) MgS04 CCI4. 

Thus, when a mixture of cydohexane 1336 (0.3 mol), oxalyl chloride (0.2 mol), and dibenzoyl peroxide (1.2 g) was refluxed for 24 h, the cyclohexanecarboxylic acid chloride 1337 was obtained in modest yield. 

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