Cyclohexaamylose structure

The rate effects imposed by this derivative, however, are dependent on the structure of the substrate. For example, the hydrolysis of 8-acetoxy-5-quinoline-sulfonate (AQS), a large substrate which cannot be included within the cyclohexaamylose cavity, is not enhanced by this derivative. Moreover, in contrast to the effects of unmodified cycloamyloses on the hydrolyses of nitrophenyl acetates, the rate accelerations imposed by this... 

Cyclohexaamylose continued) mono-6-O-tosyl-, preparation of, 23 250 pyridine-2,5-dicarboxylic acid derivative, catalytic action of, 23 251 separation of, by complexing, 23 214 structure, stereochemistry and physical properties of, 23 210-213... 

A Hyble, RE Rundle, DE Williams. The crystal and molecular structure of the cyclohexaamylose-potassium acetate complex. J Am Chem Soc 87 2779-2788, 1965. 

The steric blocking of the ortho position may be achieved in another manner. Cyclohexaamylose is a compound whose structure is akin to an open cylinder. Molecules such as anisole, C6H5OCH3,... 

There is also spectroscopic evidence about the properties of the interior of CA. Thus the spectrum of 4-tert-butylphenol complexed with cyclohexaamylose (C6A) in aqueous solution was superimposable on that of the phenol in dioxane (29), thus indicating the dioxane-like interior of the C6A cavity. Further, the difference spectrum between an aqueous mixture of C7A and N-acetyl tyrosine ethyl ester (ATEe) and ATEe in water alone was essentially identical to that between ATEe in ethyleneglycol and ATEe in water (35), which also underlines the similarity between the CA cavity and the structure of Sephadex. 

This is part V of the series Topography of Cyclodextrin Inclusion Complexes. Part IV Crystal and Molecular Structure of the Cyclohexaamylose -Propanol-4.8 Hydrate Complex , W. Saenger, R. K. McMullan, J. Fayos, and D. Mootz Acta Crystallogr. B30, 2019 (1974). 

Hybl A, Rundle RE, Williams DE (1965) The crystal and molecular structure of the cyclohexaamylose-potassium acetate complex. J Am Chem Soc 87 2779-2788 Saenger W, Jacob J, Gessler K, Steiner T, Hoffmenn D, Sanabe H, Koizumi K, Smith SM, Takaha T (1998) Structures of the common cyclodextrins and their larger analogues beyond the doughnut. Chem Rev 98 1787-1802... 

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