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Cycloheterophyllin

Activation of PKC is supposed to be a necessary prerequisite for neutrophil respiratory burst, because it mediates the phosphorylation of the proteins involved in the assembly of NADPH oxidase, which at last produces superoxide anion (02 ) from external oxygen. The isoprenylflavone cycloheterophyllin (12) isolated from Artocarpus heterophyllus (Moraceae) was known to inhibit that respiratory burst, and its interaction with PKC was therefore studied. [Pg.842]

Enzyme preparations obtained from rat neutrophil cytosol were inhibited very slightly by cycloheterophyllin, whereas those obtained from rat brain were moderately dose-dependently inhibited by the same compound at doses between 6 and 60 oM. Some degree of competition... [Pg.842]

Rama Rao, A.V., M. Varadan, and K. Venkataraman Colouring Matters of the Wood of Artocarpns heterophyllns Part VI - Cycloheterophyllin, a Flavone Linked to Three Isoprenoid Groups. Indian J. Chem. 9, 7 (1971). [Pg.192]

See other pages where Cycloheterophyllin is mentioned: [Pg.691]    [Pg.740]    [Pg.216]    [Pg.220]    [Pg.220]    [Pg.220]    [Pg.220]    [Pg.542]    [Pg.605]    [Pg.622]    [Pg.688]    [Pg.843]    [Pg.843]    [Pg.843]    [Pg.843]    [Pg.537]    [Pg.538]    [Pg.538]    [Pg.71]   
See also in sourсe #XX -- [ Pg.90 , Pg.91 ]

See also in sourсe #XX -- [ Pg.537 ]



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Isoprenylflavone cycloheterophyllin

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