Cyanocarbons

In the first study [69] of general base catalysed proton transfer from a cyanocarbon acid, the rate of detritiation of l,4-dicyano-2-butene was measured in aqueous phenolate and amine buffers. For PhO the process is 

Similar Bronsted exponents, 0.94 0.02 for phenolate ions and 0.98 0.08 for secondary amines, were observed but the Bronsted plots for these two types of catalyst were separated by about half a unit in log 0 k. The values of the Bronsted exponents are close to the limiting values of unity expected for normal proton transfer. Reaction (78) is thermodynamically favourable in the reverse direction and for fully normal proton transfer the rate coefficients for recombination of the carbanions with phenols and ammonium ions should be around 101 0 1 mole 1 sec 1. Calculations using the approximate pif 21 for this acid measured [69] in dimethyl 

Primary kinetic isotope effects in proton transfer from cyanocarbon acids in water kL  

Forward and reverse rates of ionization of malononitriles in water [64] fc) 

To test further the hypothesis that proton transfer from cyanocarbon acids is approaching normal behaviour, measurements were made [19] around ApK ca. 0 by studying the ionization of bromomalononitrile (pK° 7.81) in phosphate (pK° 7.21) and morpholine (pK° 8.49) buffers using the temperature-jump technique. The results of these experiments 

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Cyanobond Cyanoborohydride Cyanocarbon acids Cyanocarbon anions Cyanocarbons Cyanocobalamin... 

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