5- cyano valeric acid

ENZYMATIC HYDROLYSIS OF ADIPONITRILE INTO 5-CYANO VALERIC ACID, AN INTERMEDIATE FOR NYLON 6... 

For example, Bamford and Jenkins (21) polymerize a monomer in the presence of 4,4 -azo-bis-(4-cyano- -valeric acid) as initiator... 

Two AIBN-type radical polymerization initiators have been synthesized starting from commercial 4,4 -azo-bis(4-cyano)valeric acid (1) (Scheme 1) ACTP 3 -trichlorosilylpropyl-4,4 -azo-bis(4-cyano)valerate (4a) and ACTU 11 "-trichlorosilylundecyl-4,4 -azo-bis(4-cyano) valerate (4b). After thorough drying of the wet diacid 1, it was transformed into its chloride (2) using an excess of phosphorus pentachloride in dichloromethane. Reaction of 2 with the unsaturated alcohols allyl alcohol and 10-undecen-l-ol respectively gave the esters 3 in high yields which in turn led to ACTP (4a) and ACTU (4b) on Pt-catalyzed hydrosilylation. 

Isoamyl nitrite followed by a soln. of Na in ethanol cooled to —15 added at this temp, to ethyl a-carbethoxy-(3-cyanovalerate, the crude product isolated when the mixture has turned brown, dissolved in methanol, acidified with 20%-acetic acid, and treated with 3.5%-Na-amalgam ethyl a-amino-5-cyano-valerate. Y 84%. F. e. s. J. Hannart and A. Bruylants, Bl. Soc. chim. Belg. 72, 423 (1963). 

Azobis (2-methyl-N-phenylpropionamidine) dihydrochloride 2,2 -Azobis (2-methylpropane) 2,2 -Azobis (2-methylpropionamide) dihydrate 2,2 -Azobis [N-(2-propenyl)-2-methylpropionamide] 2,2 -Azobis [2-(3,4,5,6-tetrahydropyrimidin-2-yI) propane] dihydrochloride 2,2 -Azobis (2,4,4-trimethylpentane) n-Butyl-4,4-bis (t-butylperoxy) valerate t-Butyl hydroperoxide t-Butyl peroxycrotonate t-Butyl peroxyneoheptanoate Cerium Cumene hydroperoxide Cumyl peroxyneodecanoate o-Cumylperoxyneoheptanoate 1 -[(1 -Cyano-1 -methylethyl) azo] formamide Decanoyl chloride Decanoyl peroxide Di-t-amyl peroxide 2,2-Di (t-butylperoxy) butane Dicetyl peroxydicarbonate Dicyclohexyl peroxydicarbonate Dimethyl 2,2 -azobis (2-methylpropionate) 2,5-Dimethyl-2,5-di (benzoylperoxy) hexane 2,5-Dimethylhexane-2,5-dihydro peroxide Dimyristyl peroxydicarbonate Di-n-propyl peroxydicarbonate Ethyidibutylperoxybutyrate 3,3,6,6,9,9-Hexamethyl 1,2,4,5-tetraoxa cyclononane Lauroyl chloride Pelargonyl peroxide, 2-Phenylazo-4-methoxy-2,4-dimethylvaleronitrile Phosphine Potassium persulfate Sodium persulfate Succinic acid peroxide... 

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