Curcumin chemical structure

Fig. 21. The chemical structures of curcumin (enol and keto forms).

Chemical structures of reported inhibitors of HIV-1 integrase. (I) aurintricarboxylic acid monomer (II) cosalane (III) dihydronaphthoquinone or DHNQ (IV) primaquine (V) caffeic acid phenethyl ester or CAPE (VI) quercetin (VII) quercetagetin (VIII) AG1717 (IX) 3-conidendrol (X) suramin (XI) curcumin. 

A new curcuminoid, cyclocurcumin, possessing nematocidal activity, was isolated from the mother liquor by repeated purification as a yellow gum (Kiuchi et al, 1993). It had the same molecular formula as curcumin, but differed in structure by an intramolecular Michael addition of the enol-oxygen to the enone group. The chemical structures of these components are given in Fig. 6.2. 

As it can be deduced from the description of the chemical structures of anthocyans and anthocyanidins, polyphenolic pigments are usually water soluble (Figure 1). Noticeable exceptions are the curcumin oils (yellow),... 

Fig. 7.4 Chemical structures and DPP-IV inhibitory activity for the most relevant natural compounds of non-peptide nature a sulphostin b berberine c trigonelline d compound 4 e curcumin f resveratrol g luteolin h apigenin i flavone j naringin and kZINC02132035...

FIGURE 4.9 Chemical structures of curcumin (A) and thymoquinone (B). Both compounds have potent neuroprotective properties and possible anti-Alzheimer and anti-Parkinson effects. 

In this article, we have reviewed the literatures available for the mechanism of action and anti-inflammatory properties of selected nutraceuticals such as curcumin, resveratrol, green tea polyphenols and diarylheptanoids (chemical structures in Figure 1). In addition we have also shown the antiinflammatory properties of a diarylheptanoids from Alpinia galanga and different possible targets in inflammation. 

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