Curarea alkaloids from

The title alkaloids, C H NjO, were isolated from Curarea candicans by TLC. The complete structures were deduced by NMR NOEDS (544),... 

Table IV. Number of BisBIQ alkaloids isolated from the gtmeaAlbertisia, Chondodendron, Curarea, Epinetrum and Synclisia.

Later work by Marini-Bettolo et al. (449) has shed further light on the matter and the results from a series of comparative experiments have provided some support for the conclusions drawn by Biocca and Ippolito. Table 1.7 summarizes their findings. Alkaloids kept for 20 years after extraction from the fresh wood of Chondrodendron bioccai Curarea toxicofera ) greatly increased their potency on being refluxed with excess methyl iodide in methanol for 2 hours. On the other hand, extraction of another portion of the same plant material which had been stored for 20 years showed that it had lost much of its alkylatable alkaloids and attempted methylation did not... 

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