Cupric sulfate, purification

Technical-grade dimethylformamide is stirred over anhydrous cupric sulfate, filtered, and distilled under reduced pressure. The submitters used reagent-grade dimethylformamide without purification. 

There is limited evidence to recommend combined chelation and blood purification therapy for other heavy metal poisonings, such as copper, mercury, arsenic, and thalhum. There are case reports, however, outlining several such attempts. Treatment of cupric sulfate ingestion by dimercaprol and penicillamine chelation followed by hemoperfusion and hemodia-filtration has been reported [57]. An interesting case of inorganic mercury poisoning treated with DMPS chelation and continuous venous-venous hemodiafiltration (CVVHDF) was also reported [58]. It should be noted that treatment continued for 14 days with a hmited total removal of mercury (<13% of the ingested dose) in... 

Takeda T, Yukioka T, Shimazaki S. Cupric sulfate intoxication with rhabdomyolysis, treated with chelating agents and blood purification./nfem Med. 2000 39 253-255... 

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