Cross coupling reactions expansion

The ring expansion of oxyglycal-derived gm-dihalo 1,2-cyclopropanate oxyglycals provides stable seven-membered halo-oxepines, that are thus suitable precursors for further functionalizations. In a study, vinyl bromide of the bromo-oxepine was used for the metal-catalyzed cross-coupling reactions, namely, Heck, Suzuki, and Sonogashira reactions, so as to generate 2-deoxy-2-C-alkyl/ary/alkynyl septanosides [33]. 

Figure 175 The reaction sequence of cross-linking with sulfo-SANPAH involves first derivatizing an amine-containing molecule using its NHS ester end to create an amide bond. Exposure to UV light then causes ring expansion to the dehydroazepine derivative, which can couple with amines to form the final conjugate.

B4++ He reaction. This collisional system has been investigated theoretically within the framework of the semiclassical close-coupling formalism using different model potential approaches [2,3] which lead to a discrepancy of about a factor 5 for the double capture cross section values. We have thus performed an alternative study of this system by means of a full molecular expansion method, focusing our attention on the double electron capture process. 

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