Crixivan capsules

CRIXIVAN (Merck) (indinavir sulfate) capsules May 2004 labeling... 

Indinavir (IDV) Crixivan 100 mg, 200 mg, 333 mg, and 400 mg capsules Erythromycins, itraconazole, ketoconazole, fluconazole, tetracycline, dexamethasone... 

Indinavir/Crixivan (IDV) 200, 333, or 400mg capsules 800 mg q. 8h or 800 mg b.i.d. with ritonavir Nephrolithiasis, Gl intolerance, hyperbihrubinemia, metabolic complications 108... 

Indinavir. When administered with a high fai diet, indinavir (Crixivan) achieves a maximum serum concentration of V< ul the administered dose. The drug is 60% bound in the plasma. It is extensively metabolized by CYP 3A4, and seven metabolites have been identified. Oral bioavail-abiiity is good, with a of 0.8 0.3 hour. The half-life of elimination is 1.8 hour, nnd the elimination products are delectable in feces and urine. Indinavir also causes dyslipide-mm. The available dosage forms are capsules of 200, 333, and dOO mg. 

---