Critical contour criterion

FIGURE 10.75 Required initial kinematic momentum, f/p, as a function of the length of the tank, L, and the buoyancy velocity, v, when the critical contour criterion is applied with the critical concentration, C ,j, equal to 5% and the cross-drafts equal to 0.05 m s". ... 

Different regions of the variable space will often be associated with different critical peak-pairs. The resolution of a multicomponent mixture thus requires an analysis involving all components in the whole variable space. Inspection of the contour maps of global resolution will allow the evaluation of the robustness of the optimum. Figure 8.16 shows the contour maps for the separation of a set of fifteen phenols (the same cited previously in this chapter), with mobile phases of CTAB and 2-propanol, where an efficiency N = 2500 was considered for all solutes. For the positional criterion (separation factor), the optimum was found for a mobile phase of 0.12 M CTAB-10% 2-propanol (Fig. 8.16a, upper comer of the variable space), whereas for the valley-to-peak criterion it was 0.102 M CTAB-10% 2-propanol (Fig. 8.16b), and for the overlapped fi-actions, 0.107 M CTAB-10% 2-propanol (Fig. 8.16c). 

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