Crella spinulata

Benzylthiocrellidone (605) was isolated from Crella spinulata and the structure was confirmed by synthesis [479]. It is the first reported example of a natural product containing a dimedone unit [22]. 

Bandaranayake, W.M. and Wickramasinghe, W.A. (1996) Benzylmercaptan (benzylthiol) and dibenzyl-disulfide from the marine sponge Crella spinulata (Hentschell) (Poecilosderida Crellidae). Comp. Biochem. Physiol., 113B, 499-502. 

Lam, H.W., Cooke, P.A., Pattenden, G., Bandaranayake, W.M., and Wickramasinghe, W.A. (1999) Structure and total synthesis of benzylthiocrellidone, a novel dimedone-based vinyl sulfide from the sponge Crella spinulata. J. Chem. Soc. Perkin Trans. I, 847-848. 

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