Creatinol phosphate Creatinolfosfate

Hydroxypropyl cellulose Creatinol phosphate Creatinolfosfate m-Cresol... 

Hydroxypropyl cellulose Creatinol phosphate Creatinolfosfate m-Cresol Mephenesin Crotonaldehyde Tilidine HCl Crotonyl chloride Crotamiton Cupric acetate Fluocortin butyl Cupric cyanide Cyamemazine Cuprous chloride Haloprogin Cuprous cyanide Methallenestril Curare... 

Creatinol-O-phosphate can be prepared from partially hydrolysed phos-phoryl chloride and creatinol hydrobromide at room temperature [77]. Alternatively, thermal dehydration of creatinol phosphate (74) under reduced pressure gives creatinolfosfate (75) Scheme 5.18.) [77, 78]. A commercial procedure employs polyphosphoric acid in this method [79]. The drug is stable in aqueous solution at room temperature, but its isomer creatinol-A-phosphate hydrolyses rapidly to creatinol [77]. Creatinolfosfate has anti-ischaemic and antiarrhythmic properties and gives an improved ionic balance and a stronger heart beat [80]. It is useful in the clinical treatment of cardiac insufficiency and rhythm and conduction disturbances [81]. 

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