Creatinol phosphate

Hydroxypropyl cellulose Creatinol phosphate Creatinolfosfate m-Cresol... 

Then 360 kg of creatinol phosphate are added to the polyphosphoric acid continue to heat for about two hours under vacuum until the reaction water is eliminated. 

Creatinol phosphate) Use cardiac preparation, cardiac stimulant... 

Hydroxypropyl cellulose Creatinol phosphate Creatinolfosfate m-Cresol Mephenesin Crotonaldehyde Tilidine HCl Crotonyl chloride Crotamiton Cupric acetate Fluocortin butyl Cupric cyanide Cyamemazine Cuprous chloride Haloprogin Cuprous cyanide Methallenestril Curare... 

Creatinol-O-phosphate can be prepared from partially hydrolysed phos-phoryl chloride and creatinol hydrobromide at room temperature [77]. Alternatively, thermal dehydration of creatinol phosphate (74) under reduced pressure gives creatinolfosfate (75) Scheme 5.18.) [77, 78]. A commercial procedure employs polyphosphoric acid in this method [79]. The drug is stable in aqueous solution at room temperature, but its isomer creatinol-A-phosphate hydrolyses rapidly to creatinol [77]. Creatinolfosfate has anti-ischaemic and antiarrhythmic properties and gives an improved ionic balance and a stronger heart beat [80]. It is useful in the clinical treatment of cardiac insufficiency and rhythm and conduction disturbances [81]. 

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