Covers Up Prozac Withdrawal Reactions

It is most remarkable if Eli Lilly told Einbinder that it was unaware of any reports of withdrawal symptoms associated with the use of Prozac. By January 24, 1993, the SRS of the FDA had received 94 reports of withdrawal syndrome from Prozac as well as 26 reports of drug dependency and 4 of drug addiction (FDA, 1993). 

I myself made a report in the literature on Prozac withdrawal (Breg-gin, 1992b), and I sent it directly to the company as well. The company acknowledged receipt of the document (D. Marvel, personal letter, March 15, 1993) and filed it with the FDA using several event terms, including withdrawal syndrome. 

There is no way that Eli Lilly could have been unaware of reports of withdrawal reactions from Prozac. 

By the mid-1990s, there were also reports of severe withdrawal from Paxil and Zoloft. Debattista and Schatzberg (1995) reported on physical symptoms associated with a case of paroxetine withdrawal with vomiting, headache, and tremulousness, which they compared to a similar report concerning sertraline withdrawal (Louie et al., 1994). 

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