Corynespora cassicola

Methylapogalanthamine (xx), hypotensive in cats, dogs and rabbits, has adrenolytic, spasmolytic and sedative properties. It has been approved for wide clinical use in the U.S.S.rI A naphthoquinone (XXl) from the fungus Corynespora cassicola inhibits catechol-o-methyltransferase in vitro and is a hypotensive of long duration (24 hrs.) in spontaneous hypertensive rats after 12.5 mg/kg l.p. Fusaric acid (5-n-butylpicolinic acid) analogs with chlorine or bromine in the 3- and/or 4-position of the side... 

---