Corydalis aurea

Ownbey assumes on the basis of an investigation of the chromosomes that the species Corydalis aurea subsp. aurea, C. micrantha subsp. micrantha, and C. sempervirens belong to the independent section Eucroydalis, which is indigenous to northern America (835). Bohm and Gunther recommended, on the basis of the presence or absence of amurine (43c), that the section Pilosa (genus Papaver) be divided into two subsections, namely Pilosa (P. pilosum) and Pseudo-pilosa (P. atlanticum, P. latericium) (238). 

Corydalis aurea Willd. contains several alkaloids, from which a protober-berine-type base, capaurine (112), as well as a benzylisoquinoline derivative, corpaverine (previously labeled F24), have been isolated (113). Cor-... 

Capaurine and capauridine are respectively the I- and dZ-forms of an alkaloid, C21H26O5N, which has been obtained from Corydalis aurea (5),... 

Sendaverine (CXXIV), C18H21NO3 [mp 139°-140° B-HCl, mp 202°-207°], is the name given by Kametani and Ohkubo (192) to the alkaloid F-28, first isolated by Manske (193) from Corydalis aurea Willd. and which was also one of the bases present in the original sample of corpaverine (194) (Section VIII, A, 2). 

Corpaverine was the name given by Manske (193) to a base isolated from Corydalis aurea Willd. for which a definite structure was later proposed 215). A reinvestigation of the original sample lead to the conclusion that corpaverine was a mixture of the tetrahydroberberine alkaloid (— )-capaurine and a new base 194). This new base was found to be identical with alkaloid F-28 isolated by Manske from the same plant and to have an A -benzyltetrahydroisoquinoline structure. It was given the name sendaverine (Section V, A). Thermal analysis has shown that corpaverine is a molecular compound of 1 mole of (— )-capaurine and 1 mole of sendaverine (mp 136°-138°, uncorr., 139°-140° [a]i5 ° - 154.2° in CHCI3) 216). 

Corydalis ambigua Cham et Schlecht. Corydalis aurea Willd. 

Corypalline was found by Manske (40) in Corydalis pallida and in the seeds of C. aurea. The base melts at 168° picrate, m.p. 178°. 

Corydaline, C22H27O4N, was first isolated, obviously in impure form, from Corydalis tuberosa by Wackenroder (242). It has since been found in C. ambigua (24), C. aurea (28), C. Montana (29), and C. platycarpa (46). It crystallizes from hot methanol in stout hexagonal prisms and has... 

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