Corticosteroids—glucocorticoids long-term effects

The glucocorticoids also have powerful anti-inflammatory effects and when first introduced were considered to be the ultimate answer to the treatment of inflammatory arthritis. Unfortunately, the toxicity associated with chronic corticosteroid therapy limits their use except in the control of acute flare-ups of joint disease. Therefore, the nonsteroidal anti-inflammatory drugs have assumed a major role in the long-term treatment of arthritis. 

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