Corticosteroids clinical uses

The predominant clinical use of corticosteroids is a result of their associated antiinflammatory properties. These are commonly used as topicals for the suppression of symptoms, including inflammation, occurring in a particular disease state these compounds are rarely considered curative in their usage. Many other disease states do, however, respond well symptomatically to treatment with corticosteroid therapy. Some of these (11) are Us ted below. 

The reformulation of beclomethasone MDI formulations using HFA propellants has provided us with some insight as to the relationship between the particle size and the aerosol velocity of corticosteroids delivered by MDI and their clinical effect. Particles generated from an HFA-MDI containing the newly formulated beclomethasone aerosol primarily are composed of 1.1- to 2.1-pm particles, compared to 3.3- to 4.7-pm particles generated by the older CFC-MDI (59). At the same time. 

Buljevac et al. (2005) have recently published a case report concerning an 18-year-old patient with the serosal form of the disease. Basal US visualised nodular peritoneal deposits associated with ascites, whose cytological sampling revealed the presence of numerous eosinophils. After 2 weeks of corticosteroid treatment, the clinical, laboratory and US findings normalised (Buljevac et al. 2005). 

Peroneal tendon tears can be observed in patients following ankle sprains or with a history of chronic instability, especially if they are affected by systemic disorders such as rheumatoid arthritis and diabetes mellitus or are receiving corticosteroids (Kraus and Brodsky 1998 Wang et al. 2005). Clinically, the rupture of peroneal tendons leads to inability to evert and cavovar us foot Tears of the peroneus brevis tendon are most common and present with a typical longitudinal configuration, commonly referred to as split or fis-... 

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