Fatigue cortical bone

P. Zioupos, M. Gresle, K. Winwood, Fatigue strength of human cortical bone age, physical, and material hetert eneity effects, J. Biomed. Mater. Res. A 86 (2008) 627-636. 

Carter, D. R., Caler, W. E., Spengler, D. M., and Frankel, V. H. (1981), Fatigue behavior of adult cortical bone The influence of mean strain and strain range, Acta Orthop. Scand. 52(S) 481-490. 

Choi, K. and Goldstein, S.A. (1992) A comparison of the fatigue behavior of human trabecular and cortical bone tissue. J. Biomech., 25, 1371-1381. 

However, some other orthopedic implantable medical devices including carbon fiber have shown successful results. Carbon-fiber-reinforced polyetheretherketone (CFR-PEEK) has been reviewed by Li et al. [13] to assess properties, technical data, and safety in orthopedic applications. CFR-PEEK may be an ideal material as it has a modulus very similar to bone and an ability to withstand prolonged fatigue strain. It can also be manufactured to match the modulus of both cortical and cancellous bone densities. This review shows no breakdown over time, while CFR-PEEK is readily accepted by the body. One reported study done by Steinberg et al. [48] makes a comparison between commercially available devices and CFR-Peek substitutes for wear/debris. The wear/debris was assessed based on the amount of the debris generated... 

---