Correspondence Between Surface Pore Dimensions from AFM and MWCO

Such cell probes allow the direct meastirement of the adhesion of biological cells to membranes. Interpretation of the data for such cell probes is more difficult than for colloid or modified colloid probes, as the cell can distort during the measurements. However, the data show that the XP117 development membrane has lower adhesion and hence lower fouling propensity, also for yeast cells. 

Con-espondence Between Surface Pore Dimensions from AFM and MWCO 

From a practical point of view, the choice of ultrafiltration membranes for a particular process is usually defined in terms of MWCO, defined such that solutes of such molecular weight would be 90% rejected by the membrane. Care is required in the use of MWCO, as rejection can depend on other factors such as charge and molecular shape, but it remains an extensively used parameter. It is possible to estimate the mean pore diameter of membranes from rejection data such as MWCO through the use of an appropriate mathematical expression. As MWCO is an historically important measure and AFM a relatively new technique it is pertinent to investigate the correspondence between the data respectively obtained. 

GE (MWCO 1000) and GN (MWCO 10000) at low resolution (above) and high resolution (below). 

Indeed, there is a significant increase in surface roughness throughout the range, as shown by the data in Table 6.1. 

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Correspondence between surface pore dimensions from AFM and MWCO is good. In addition, AFM gives surface pore size distribution. 

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