Correlation Between ORD and CD

CD but CD is much more sensitive than ORD because the trailing parts of the ORD curves representing Cotton effects often overlap. 

Both ORD and CD are sensitive to conformational changes and chemical transformation. ORD has the following advantages over CD (1) It is easier to visualize the Cotton effect with ORD because of the three distinct points in the ORD curve the peak, the crossover, and the trough (in that order or in reverse order). (2) An optically active compound that does not show the band in the wavelength range of interest in the absorption spectrum will not show a CD curve but will show a plain ORD curve. CD, on the other hand, possesses an intrinsic discreteness and is a more sensitive tool in examining the environmental effect on the conformation of macromolecules. 

A reciprocal relationship exists between ORD and CD using the Kronig-Kramers (Kronig, 1926 Kramers, 1927) transform  

The prime ( ) represents the assigned vacuum values (see Moscowitz, 1960). The condition attached to this transform is that the rotatory dispersion curve must be Gaussian. Thus, from the CD curves, we can calculate the rotatory dispersion and vice versa. 

---