Cornea Fuchs

Fuchs (endothelial) dystrophy has a component of guttata, but the involvement is such that corneal physiology is affected adversely. Fuchs dystrophy occurs bilaterally, has been reported to be transmitted dominantly (with incomplete penetrance), and females are three times more likely to develop the condition. Prominent guttata initially occur centrally and then become extensive enough to involve the peripheral cornea. In Fuchs dystrophy the... 

Yuen HK, Rassier CE, Jardeleza MS, et al. A morphologic study of Fuchs dystrophy and bullous keratopathy. Cornea 2005 24 319-327. 

Regarding OVD application with intraoperative complications, tissue stability and movement must be differentiated from selective tissue isolation (Fig. 53). Healon 5, Healon GV, Microvisc (Plus), Morcher Oil (Plus), Viscorneal (Plus) (identical to Allervisc (Plus) in content), and other viscoelastic substances are considered suitable to counter a flattened anterior chamber, widen a small pupil, simplify a complicated capsulorhexis, resolve synechiae, or counter iridal and vitreous prolapse (Fig. 54). Endothelial dystrophy (Fuchs Dystrophy, advanced cornea guttata), torn posterior capsule or vitreous prolapse are particularly well suited for Viscoat application (followed by AMO Vitrax , HPMC Ophta H, Visco Shield , and other HPMC products). These viscoelastics are preferred substances in case of zonular dialysis with vitreous body prolapse or sinking nucleus (Fig. 55). 

French DD, Margo CE. Postmarketing surveillance of corneal edema, Fuchs dystrophy, and amantadine use in the Veterans Health Administration. Cornea 2007 26 1087-9. 

Fuchs K, Bonjer K-P, Bock G, Cornea I, Radu C, Enescu D, Jianu D, Nourescu A, Merkler G, Moldoveanu T, Tudorache G (1979) The Romanian earthquake of March 4,1977. II. Aftershocks and migration of seismic activity. Tectonophysics 53 225-247... 

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