Corey-Gilman-Ganem oxidation

This reaction was first reported by Corey and co-workers in 1968. It is an efficient synthesis of o ,j8-unsaturated esters by treatment of o, j0-unsaturated aldehydes (or allyl aicohois) with manganese dioxide and potassium cyanide in a proper alcohol. This reaction is thus known as the Corey-Gilman-Ganem oxidation in general or simply the Corey-Ganem oxidatin. ... 

It is believed that this reaction involves the formation of cyanohydrins, which are then converted into the corresponding acyl cyanides the acyl cyanides are subsequently transformed to either acids or esters in the presence of appropriate solvents, such as acetic acid or methanol.A tentative illustration of the mechanism for the Corey-Gilman-Ganem oxidation is thus given here. 

Other references related to the Corey-Gilman-Ganem oxidation are cited in the literature. ... 

---