Coreceptors heterotopic

Heterotopic Coreceptors — Cyclophane Receptors, Amphiphilic Receptors, Large Molecular Cages... 

Supramolecular metallocatalysts consist in principle of the combination of a recognition subunit (such as a macrocycle, a cyclodextrin, a cyclophane, etc.) that selects the substrate(s) and of a metal ion, bound to another subunit, that is the reactive site. Complexed metal ions presenting free coordination positions may present a variety of substrate activation and functionalization properties. Heterotopic coreceptors such as 70 bind simultaneously a substrate and a metal ion bringing them into proximity, thus potentially allowing reaction between them. 

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