Copper, reaction with dibromodifluoromethane

A similar distribution of copper reagents can be obtained via the du ect reaction of copper metal with dibromodifluoromethane or bromochlorodifluoromethane in DMF at 85-95 °C [2J2] The oligomerization can be supressed via the addition of alkali metal fluorides to the reaction mixture [272] When HMPAis added to the trifluoromethylcopper solution, decomposition is slowed, and this solution can be used to trifluoromethylate aromatic iodides [270] (equation 143). 

Reaction of Dibromodifluoromethane and 4-Chloro-3-nitrobenzotrifluoride with Copper... 

Tetrafluoroethylene was the only fluorine-containing product obtained from attempted coupling reactions with 1,2-dibromo- and 1,2-diiodotetrafluoroethane, and dibromodifluoromethane, perhaps via unstable copper compounds 200). 

A. (1,3-Dibromo-3,3-difluoropropyl)trimethylsilane (Note 1). A 250-mL pressure tube (Note 2) equipped with a magnetic stirring bar is charged with vinyltrimethylsilane (20 g, 30.8 mL, 0.20 mol), ethanolamine (6.11 g, 6.04 mL, 0.10 mol), dibromodifluoromethane (83.9 g, 36.5 mL, 0.4 mol), copper(l) chloride (0.18 g, 1.8 mmol), and tert-butyl alcohol (15 mL) (Notes 3 and 4). The tube is sealed and stirred for 20 hr in an oil bath at 90°C (Note 5). The reaction mixture is combined with that from another run at the same scale and diluted with 40 mL of hexane (the mixture separates into a cloudy supernatant and a brown resin). The hexane layer is... 

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See also in sourсe #XX -- [ ]

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