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Controlled release systems enzyme-modulated

The cytotoxic hypoxia of acute CN intoxication affects the energy-dependent processes controlling cellular ionic homeostasis and the ionic disequilibrium normally maintained between the intracellular and extracellular fluid compartments (Maduh et al., 1993). In isolated cell preparations, the cellular ionic disruption results in marked cellular acidosis and accumulation of cytosolic Ca++ (Bondy and Komu-lainen, 1988 Li and White, 1977 Nieminen et al., 1988). This may result in disturbances of Ca++-activated lipolytic enzyme activity, peroxidation of membrane phospholipids, changes in transmitter release and metabolism and effects on other Ca++-modulating cell signaling systems. Johnson etal. (1986) found that CN significantly... [Pg.510]

See other pages where Controlled release systems enzyme-modulated is mentioned: [Pg.2034]    [Pg.70]    [Pg.113]    [Pg.343]    [Pg.341]    [Pg.1158]    [Pg.1120]    [Pg.193]    [Pg.221]    [Pg.326]    [Pg.55]    [Pg.60]    [Pg.1120]    [Pg.376]    [Pg.194]    [Pg.91]    [Pg.128]    [Pg.230]    [Pg.72]    [Pg.304]    [Pg.117]    [Pg.334]    [Pg.329]    [Pg.679]    [Pg.83]    [Pg.220]    [Pg.134]    [Pg.376]    [Pg.120]   
See also in sourсe #XX -- [ Pg.22 , Pg.23 ]



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Control module

Controlled release

Controlled-release systems

Enzyme modulation

Enzyme release

Enzyme systems

Enzyme-controlled systems

Enzymes , control

Enzymes modulators

Enzymic Control

Modulated release

Modulator enzymes

Release modulators

Release system

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