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Gastrointestinal tract, controlled-release delivery systems

Klokkers-Bethke K, Fischer W. Development of a multiple unit drug delivery system for positioned release in the gastrointestinal tract. J Control Release 1991 15 105-112. [Pg.396]

The direct transport of absorbed drugs into systemic circulation, effectively by-passing the first-pass effect of the liver and gastrointestinal tract Lower enzymatic activity compared to the gastrointestinal tract or liver Amenability to self-medication, which increases patient compliance Possibility of pulsatile delivery of some drugs to simulate the biorhythmic release of these drugs Lower risk of overdosage Achievement of controlled release... [Pg.113]

See other pages where Gastrointestinal tract, controlled-release delivery systems is mentioned: [Pg.354] [Pg.235] [Pg.553] [Pg.283] [Pg.93] [Pg.41] [Pg.454] [Pg.119] [Pg.77] [Pg.78] [Pg.86] [Pg.210] [Pg.111] [Pg.420] [Pg.425] [Pg.74] [Pg.138] [Pg.148] [Pg.59] [Pg.160] [Pg.236] [Pg.780] [Pg.991] [Pg.992] [Pg.1093] [Pg.1850] [Pg.325] [Pg.308] [Pg.513] [Pg.119] [Pg.216] [Pg.383] [Pg.122] [Pg.275] [Pg.555] [Pg.687] [Pg.404] [Pg.29] [Pg.183] [Pg.92] [Pg.697] [Pg.150] [Pg.270] [Pg.674] [Pg.36] [Pg.115] [Pg.499]

See also in sourсe #XX -- [ Pg.121 , Pg.126 ]

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