Controlled release applications advantages over encapsulation

In the context of controlled release, the layer-by-layer fabrication procedure offers potential advantages over conventional protein and nucleic acid encapsulation strategies, including the ability to control the order and location of multiple polymer layers with nanometer scale precision, and the ability to define the concentrations of incorporated materials simply by varying the number of polymer layers incorporated [190-192]. Although numerous reports describe the application of these materials to the sustained release of permeable small molecules [193-197], there are few examples of these assemblies designed to release macromolecular components. Several groups have performed... 

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