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Controlled drug delivery system thermo

I. Colombo, M. Grassi, M. Fermeglia, R. Lapasin and S. Pricl, Modeling phase transitions and sorption desorption kinetics in thermo-sensitive gels for controlled drug delivery systems, Fluid Phase Equil., 1996, 116, 148-161. [Pg.214]

A very intriguing development concerns a drug delivery system for the treatment of periodontitis. It consists of two components. The first is a clay product loaded with tetracycline. The clay product is coated with chitosan to retard drug release. The second component is a thermo-responsive polymer mixed with polyethylene glycol that is syringable at room temperature but solidifies upon warming up to body temperature. The solidified polymer remains 60 min in situ. After that time, it still inhibits the formation of bacterial colonies, and still contains much more of the antibiotic than the control containing no chitosan. [Pg.287]


See other pages where Controlled drug delivery system thermo is mentioned: [Pg.577]    [Pg.269]    [Pg.97]    [Pg.277]    [Pg.393]    [Pg.62]    [Pg.212]    [Pg.221]    [Pg.23]    [Pg.512]    [Pg.169]    [Pg.1731]    [Pg.23]    [Pg.113]    [Pg.354]    [Pg.113]    [Pg.67]    [Pg.56]    [Pg.115]    [Pg.3]    [Pg.28]    [Pg.509]    [Pg.3]    [Pg.28]   
See also in sourсe #XX -- [ Pg.114 , Pg.413 ]




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