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Controlled delivery polymer wafer

Gliadel - a controlled-delivery polymer wafer is the combination of a copolyanhydride matrix consisting of CPP and sebacic acid (20/80 mol. ratio) in which an anticancer agent is physically admixed. Clinical investigations of Gliadel implants in rabbit brains have shown limited toxicity, initial activity and fast excretion of decomposition products as free acids (J4). [Pg.20]

MAJOR APPLICATIONS Biodegradable polymer for controlled drug delivery in a form of implant or injectable microspheres (e.g., Gliadel -BCNU-loaded wafer for the treatment of brain tumors). [Pg.303]


See other pages where Controlled delivery polymer wafer is mentioned: [Pg.14]    [Pg.5]    [Pg.103]    [Pg.2255]    [Pg.15]    [Pg.157]    [Pg.524]    [Pg.88]    [Pg.23]    [Pg.38]    [Pg.34]    [Pg.196]    [Pg.38]    [Pg.537]   
See also in sourсe #XX -- [ Pg.20 ]




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