Contrast-induced nephropathy pathogenesis

Heinrich M, Uder M. Pathogenesis of contrast-induced nephropathy. AJR Am J Roentgenol 2005 185 1079 author reply 1079. 

The use of iodinated contrast media (CM) continues to be a common cause of hospital-acquired acute renal failure (ARF) and its development increases the in-hospital mortality significantly [1, 2,3, 4] as well as increasing the length of hospital stay [5]. Contrast media-induced nephropathy (CMIN) is defined as an otherwise unexplained acute deterioration of renal function after intravascular administration of iodinated CM. Although the clinical features and the histopathological findings of CMIN have been well described [6-9], its pathogenesis, prevention and best treatment modality remain uncertain. 

I 8 Goldenberg I, Matetzky S. Nephropathy induced by contrast media pathogenesis, risk factors and preventive strategies. CMAJ 2005 172 1461-1471. 

---

See also in sourсe #XX -- [ ]

---