Contact allergy provocative test

Case reports of allergic contact dermatitis from alcohols were recently reviewed (Ophaswongse and Mai-bach 1994)- In addition, cross reactivity and oral provocation were addressed. An individual with a type-IV allergy may cross react to other alcohols on patch testing. In a few cases, oral provocation with alcoholic beverages was positive, but it is unclear whether there was a coexistence of type I and type IV in some patients. There are presumably metabolic dose-response relationships and individual susceptibility factors that operate as risk factors in predicting one s propensity to develop systemic contact dermatitis due to oral provocation. 

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