Construction of the Imidazole Ring

There are a variety of imidazole syntheses, some of which have names attached to them. A survey of these reactions will be overviewed followed by more modem modifications of syntheses. 

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Construction of the imidazole ring onto a triazine has been also used for the synthesis of this group of compounds. The reaction of 3-aminobenzofl, 2,4]triazine with a-bromoacetaldehyde acetal gave the [1,2-b] linear isomer. On the other hand, the similar reaction on 1-oxide 461... 

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